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Natural selection will eliminate coding regions repaired by inaccurate mechanisms, accounting for the low mutation rates in genes, whereas mutations, rearrangements, and expansions generated by inaccurate repair in noncoding regions will persist.
We obtained these for the March 2006 release of the human genome and subjected them to a variety of filters to eliminate coding sequence, potential mis-alignments, and regions of low sequence quality (see Methods).
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We eliminated coding sequence using the UCSC genome informatics group's table browser [ 26].
We eliminated coding sequences that did not start with ATG, did not finish with a stop codon (TAA, TAG, and TGA), had internal stop codons, were not a multiple of three long, or contained one or more ambiguous nucleotides ("N").
We verified and rejected the occurrence of every indel (presumably deriving by sequencing errors), by examining the corresponding ESTs and re-estimated diversity after reintroducing the erroneously eliminated coding regions.
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When dynamic bandwidth allocation is not used, code reassignments are needed to eliminate code blocking only.
Furthermore, we confirmed the results after eliminating coding sequences contained in promoter sequences, as follows.
Both CBP and CBR also undertake reducing the number of code reassignments while eliminating code blocking.
3) Then, transcripts were compared to the Swiss-Prot protein database to eliminate protein coding transcripts using BlastX with an E-value cutoff of 1E-03.
The influence of complications due to the inpatient process of care can be eliminated by coding risk adjusters based on the pre-index date claims (i.e. the fourth analytical file in our study).
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