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Here again, SCTP is an eligible protocol.
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Of 894 eligible protocols of randomised controlled trials involving patients (figure), 252 (28.2%) planned at least one subgroup analysis.
We plan to extract 30% of eligible protocols independently and in duplicate and conduct random checks for consistency in remaining protocols.
In the therapy selection setting, the patient can be eligible for protocol treatment in an intensified alkylating chemotherapy study (for example, trial NCT01057069 [ 28]).
18 Twelve investigators trained in clinical research methodology independently extracted data from eligible trial protocols and correspondence between the research ethics committees and the local investigators.
Based on information by the collaborating RECs and published data, we anticipate that we will identify over 1000 eligible RCT protocols approved by the participating RECs between 2000 and 2002/3 and that about 15% of these RCTs were discontinued due to insufficient recruitment.
The immunogenicity analyses were performed on the per-protocol immunogenicity cohort including all eligible subjects without protocol deviation who had serological data available at a given time point (Day 0, Day 21, or both).
This left 209 patients (61.1%) with AUFI eligible for the protocol.
All consecutive adult patients (>18 years) admitted to the ICU within 24 hours of onset of septic shock were considered eligible for this protocol.
Of the 282 patients, 197 patients were eligible for the protocol 9904 3) phase II clinical trial.
Only patients who mantained the hemodynamic stability during the assessment period were eligible for the protocol administration.
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