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Two reviewers independently assessed trial eligibility and quality of randomized controlled trials.
Those who pass a preliminary screening for eligibility and quality will then be invited to submit a more detailed proposal.
Studies were evaluated for eligibility and quality, and data were abstracted on study design, demographics, intervention or predictor factor, and cognitive outcomes.
Two authors independently assessed trial eligibility and quality.
Two reviewers independently assessed eligibility and quality of the studies.
A systematic search followed by assessment of eligibility and quality.
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The eligibility criteria and quality scoring were assessed by two independent investigators.
The pre-publication history for this paper can be accessed here: http://www.biomedcentral.com/1471-2318/14/27/prepub We thank Dr. Hans Reitsma for his advice on the possibilities of performing a meta-analysis, and we thank Dr. Saskia Weldam for her suggestions on the eligibility criteria and quality assessment.
Two authors (P.K.B and N.L) independently reviewed the data and assessed the eligibility and methodological quality of each eligible trial.
Data extraction Two reviewers evaluated eligibility and methodological quality.
Data collection and analysis Three independent reviewers assessed eligibility and trial quality and extracted published data.
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