Exact(2)
In contrast to other agents able to induce apoptosis, Ca2+ ionophore A23187 elicits direct activation of intracellular signal(s).
While CB1 functions mainly through modulation of central and peripheral neurotransmitter release, activation of CB2 elicits direct anti-inflammatory effects in target cells [ 33].
Similar(58)
Therapeutic vaccines employing new technology, vectors and new immunomodulatory drugs that can elicit direct antiviral effects and cancel inhibitory mechanism may be able to overcome exhaustion.
From a nationally representative sample, we elicit direct values for the three pairwise trade-offs between travel time, travel cost, and safety.
Treatment with PYRRO-C3D (a representative C3D containing the diazeniumdiolate NO donor PYRRO-NO) was found to significantly reduce viability of planktonic and biofilm pneumococci, demonstrating that C3Ds can elicit direct, cephalosporin-like antibacterial activity in the absence of β-lactamases.
Besides its effects on leukocyte transmigration, Natalizumab may elicit direct effects on T cell function.
Firstly, those studies were constructed so to elicit direct social comparisons between individuals by either manipulating participants' specific information or by having individuals playing on same trials.
This mammalian source of recombinant and soluble IL-24 has previously been reported to elicit direct apoptosis as well as bystander effects in melanoma and other cancer cells [30], [34] while other studies failed to detect these effects [33], [43].
However, in vitro evidence shows that ZD6474 can also elicit direct inhibition of tumour cell growth (Arao et al, 2004).
In addition, the American Medical Association and the Canadian Orthopaedic Association recommend using direct questions because they are easy to understand and tend to elicit direct responses [ 15, 44].
In contrast to other agents able to induce apoptosis of cultured cells, Ca2+ ionophore A23187 was shown to elicit direct activation of intracellular signal(s).
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