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Despite the observation that many repressive chromatin factors are implicated in Xi establishment and maintenance, interference with DNA methylation has thus far shown the largest effect on eliciting loss of gene silencing on the Xi [ 5, 9, 14].
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Reductions in CBFV (potentially exacerbated by impaired autoregulation or OH) can precipitate symptoms of orthostatic intolerance and may elicit loss of postural tone through a syncopal episode, which can present as a fall-like event [ 3].
This shorter duration of exercise may be a more efficient alternative for eliciting fat loss than MICT.
The increase in MT-1E mRNA appeared to be influenced mainly by exposure to the various metals, whereas the increase in MT-1A mRNA was influenced more by exposure to a metal concentration eliciting a loss of cell viability.
In keeping with this, ICV administration of the specific ERα agonist PPT (Sánchez-Criado et al., 2004, 2006; Roa et al., 2008) to OVX rats recapitulated the effects of E2 by eliciting weight loss and anorexia, associated with increased UCP1 expression in BAT and reduced AMPK signaling in the VMH.
In a recent position statement from the Academy of Nutrition and Dietetics [ 37], four dietary strategies for eliciting weight loss in overweight and obese youth were recommended: (1) modified traffic light diet [ 42], (2) low carbohydrate diet [ 41, 43, 44], (3) reduced glycaemic load diets [ 45, 46] and (4) non-diet approach [ 47, 48, 49, 50].
2018 Jan 25 553 7689):461-466. Epub 2018 Jan 17. Haley et al. Podocyte injury elicits loss and recovery of cellular forces.Sci Adv.
In contrast, high concentrations of ethanol elicit loss of postural control and eventually sedation (Moore et al. 1998; Rothenfluh et al. 2006; Corl et al. 2009).
Moreover, Mst loss causes a mutant phenotype indistinguishable from that elicited by loss of any TCP-1 subunit, and the biochemical properties of extracts depleted of either Mst or TCP1-α are identical.
In the aged group, MDMA elicited heterologous loss of adenylyl cyclase responses instead of displaying the supersensitivity that had been seen in the young group.
Furthermore, in Yfh1, a R141A mutation which should elicit the loss of the π interactions between W131 and R141, had no effect on the interaction with Isu1 [13].
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