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This was further confirmed with an elevation of the expression of AKT and of NFkB (not shown).
In comparison with vector transfected controls, 16Q-TBP transfected cells showed marginal elevation of the expression levels of all the genes tested.
These experiments revealed a significant elevation of the expression of myosin heavy chain I (MyHCI, 1.7 fold) and myosin heavy chain IIx (MyHCIIx, 2.0 fold), whereas transcription of myosin heavy chain IIa and IIb (MyHCIIa and MyHCIIb) was unchanged (Fig. 5A).
Therefore, the elevation of the expression of the miR-23a/b and miR-27a/b clusters may suppress the neuronal apoptosis induced by pathological injuries.
We observed an elevation of the expression of HMGR with the depletion of the mitochondrial genome (LN ρ0-8) could be attenuated with the reconstitution of the genome (LNCyb).
However, deletion of rutR alone does not result in a significant elevation of the expression levels of most of its target genes, suggesting that RutR regulates target gene transcription via a different mechanism.
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As expected, limiting the expression of c-Jun caused elevation of the expressions of epithelial marker E-cadherin and concomitantly reduction in the expression of mesenchymal markers N-cadherin and vimentin in KB/VCR cells, paralleling to the observations achieved via interference with JNK1/2 by pharmacological and shRNA approaches.
The mRNA expression was also analyzed; patients with refractory convulsive status epilepticus had an elevation of the mRNA expression for the α2 subunit (GABAA receptor) and patients with refractory epilepsy had an elevation of the mRNA for the α2 subunit and of the α2/α1 ratio (GABAA receptor) [ 17].
This may be explained by the observed significant elevation of the PPARG expression.
The elevation of the PR5 expression without Pst T1 inoculation may be related to wounding stress by syringe infiltration.
Longitudinal studies demonstrated that the increase in circulating IL-6 preceded a significant elevation of the gene expression of Socs3 and Il-6ra.
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