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Therefore, the main purpose of this paper is to address the gap by providing an elevated understanding of CCM and its consequences.
Up to this point much emphasis has been put on understanding the 'transcriptional plane' of the p53 network, but, as illustrated in this review, an increasing understanding of the 'post-transcriptional plane' of the network will be necessary for an elevated understanding of the roles of p53 in tumor suppression and, consequently, in the development of p53-based therapies.
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We may naturally wish for a larger story, a greater understanding, an elevated view.
The analysis of the micro-structural scenarios that cause variation of strain and stress is the first step in understanding the elevated strains and stresses in bone tissue, which are indicative of higher likelihood of micro-crack formation in bone, implicated in consequent remodeling or macroscopic bone fracture.
The current studies were aimed at further understanding how elevated neuronal MHCI levels affect neuronal connections using an in vitro embryonic retina-thalamic co-culture system.
Targeted therapy with mTOR inhibitors in RCC was based on the understanding that elevated HIF could induce the PI3K/AKT pathway and promote angiogenesis [ 124].
Paradoxically, the positive association between autonomic anxiety and CVC in the preset study subverts the typical understanding that elevated anxiety accompanies sympathetic activation and parasympathetic withdrawal.
It is quite true that the understanding of elevated GGT values is very limited, despite the fact that this value is one of the most requested 'liver function tests'.
Understanding how elevated temperatures and nutrient concentration affect early transcriptional changes in corals and their algal endosymbionts is critically important for evaluating the responses of coral reefs to global changes happening in the environment.
Therefore, patients with high CEA concentration after surgery should be thoroughly studied with the understanding that elevated CEA often, but not always, predicts the recurrence of CRC (Filiz et al, 2009).
Understanding how elevated CO2 may affect the major traits of turfgrass growth and water use efficiency provides guidelines for how to develop efficient management tactics, such as irrigation, to maintain quality turfgrass in the scenario of increasing CO2 concentration in the future.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com