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Although normal or even elevated levels of TFPI can be found in DIC and sepsis, elevated tissue factor levels can be measured in the plasma of these patients, suggesting a relative deficiency of TFPI to neutralize tissue factor, which finally results in unopposed thrombin generation [ 80].
Elevated tissue antibody responses were not associated with differences in growth.
Elevated tissue glycerol levels indicate cell membrane damage.
Therefore, it seems reasonable to suggest that therapeutic regimes of high-dose statin could lead to considerably elevated tissue accumulations of the drug, especially when considering the lipophilic nature of these compounds.
We also detected elevated tissue mRNA levels of IL-17A in leading edge skin biopsies of vitiligo patients, as well as IL-17A positive T cells by immunohistochemistry and immunofluorescence.
Additionally, elevated tissue levels of Cu (34.77 ng/mg in testis) and Zn (831.85 ng/mg in digestive gland, 83.96 ng/mg in testis) nearshore are similar to reported levels resulting in reproductive inhibition in other gastropods, indicating that these metals possibly contribute to NS conch reproductive failure.
To test, whether elevated tissue expression of prohepcidin in the gallbladder epithelia is also translated into increased biliary hepcidin levels, we measured prohepcidin peptide levels in PSC patients with and without a bacterial cholangitis using a previously established prohepcidin ELISA assay [19].
CDC has reported elevated tissue viral loads in 2 necropsied prairie dogs (18 ).
For instance, many cancers such as breast cancer have elevated tissue stiffness due to altered ECM composition.
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These elevated tissue-specific expression levels might represent an adaptation to the increased needs for membrane recycling in secretory cells or cells undergoing morphogenesis and shape changes.
Thus, the stabilized and elevated tissue-specific levels of CI, CII, CIII and CV activities and elevated coupled CI - CIII and CII - CIII activities are unique physiological ETC characteristics of the kidney in long-lived dwarf mice that are established and maintained throughout the post-natal dwarf life cycle.
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