Sentence examples for elevated susceptibility from inspiring English sources

Localized myocardial copper deficiency was accompanied by decreased expression and increased polymerization of the copper-responsive transition-metal-binding metallothionein proteins (MT1/MT2), consistent with impaired anti-oxidant defences and elevated susceptibility to pro-oxidant stress.

Most of the newborn children and some pregnant women in this Latino cohort may have elevated susceptibility to organophosphate toxicity because of their PON1 192 genotype and low PON1 plasma levels.

Mice bearing a knockout allele of Atm and humans carrying a mutant allele of truncated type in the ATM gene have been shown not to have obviously elevated susceptibility to mammary carcinogenesis.

Previous research has almost exclusively been performed in European origin populations, and may not extrapolate to other ethnic groups, such as South Asians, where escalating rates of tobacco consumption will impact adversely on an already elevated susceptibility to cardio-metabolic disease [ 12].

Our data that PINK1 deficiency becomes more evident under cell stress might explain the elevated susceptibility of dopaminergic nigrostriatal neurons in PINK1-linked Parkinsonism, since these neurons are known for high levels of oxidative stress from dopamine metabolism.

Besides, subjects with lower percentage of urinary DMA also showed an elevated susceptibility to hypertension.

Although extrapolating such experimental data to human exposures should be done with great caution, our findings suggest that cellular and biochemical changes associated with chronic oxidant stress, frequently encountered in highly polluted areas, may significantly elevate susceptibility to some co-pollutants, thereby posing a greater risk to human health.

In summary, loss of Cdk5 for 2 months led to increased lethality, elevated seizure susceptibility, and electrographic evidence of seizure activity.

Mutations altering BLM function are associated with highly elevated cancer susceptibility (Bloom syndrome).

Later maturing genotypes showed on average a higher specific gravity and elevated bruising susceptibility.

Several studies reported that inbreeding might also elevate the susceptibility to diseases [19], [20], [22] and thus suggested a correlation between susceptibility and low fitness due to inbreeding.