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Eighty-eight generally healthy adults with ≥1 elevated risk factor for cardiovascular disease were randomized in a single-blind (diets)/double-blind (supplements), parallel-group study for 8 weeks.
As a result we could not assess whether physicians responded immediately to a visit of an elevated risk factor level.
These findings might be explained by low rates of medication initiation and dose adjustment in patients with elevated risk factor levels [ 11, 13, 14].
A high number of disease cases might be due to a common elevated risk factor of limited geographical or temporal extension.
This approach has been recommended in the cardiovascular risk factor management guidelines for young women with elevated risk factor levels [ 23].
The main outcome measures were the proportion of participants with CVD risk factors with group comparisons to determine the adjusted likelihood of elevated risk factor levels.
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On the contrary, adults with Down syndrome seem to be protected against atherosclerosis, despite having elevated risk factors, such as elevated total body fat, higher levels of triglycerides and C-reactive protein, and lower levels of moderate to vigorous physical activity [24].
Individuals who have elevated risk factors early in life have an increased risk of CVD.
Previous studies have also reported that it is difficult for individuals to exceed the recommended treatment thresholds even with markedly elevated risk factors.
Intensity of disease management (in 2000) did not appear to affect racial/ethnic disparities in risk factor control, flu vaccination rates, or intensity of medication management for elevated risk factors either positively or negatively (54).
The metabolic syndrome, including elevated risk factors such as obesity, dyslipidemia, and insulin resistance, increases the risk of later cardiovascular disease by approximately two-fold and quadruples the risk of developing type 2 diabetes (Meigs 2002).
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