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Elevated lipase levels are common in NE and may reflect a more severe form of NE.
The most common reasons for dose reduction were anemia (n=5) and elevated lipase levels (n=4).
Elevated lipase levels were common in our patient cohort and might reflect a more severe form of NE.
Furthermore, almost 40% of patients under 3 years of age with a diagnosis of acute pancreatitis were reported to have normal amylase but elevated lipase levels [ 19].
Of the 166 patients, 25 (15 %) had elevated lipase levels at the time of admission to hospital or first contact with general practitioner/nephrologist. In total 7 patients had a threefold increased serum lipase above the normal range.
In these patients, elevated lipase levels should no lead to misdiagnose acute NE, but acute pancreatitis must be considered if enzyme levels are more than threefold normal in association with clinical manifestations.
Similar(47)
Her level of pancreatic enzymes was also elevated: lipase level was 194 IU/L (normal 7 60 IU/L) and phospholipase A2 level was 1,340 ng/dL (normal 130 400 ng/dL).
In our patient cohort, 15%% of the patients had elevated serum lipase levels at time of diagnosis and 7 patients had a threefold increased serum lipase above the normal range.
LFT's were not elevated and lipase level was normal at 30 U/L.
12 The diagnosis of AP was as follows: (1) prolonged abdominal pain characteristic of AP; (2) elevated serum amylase (Amy) and/or lipase levels by at least threefold that of normal range and (3) characteristic findings of AP on abdominal ultrasonography and/or CT scan.
Serum amylase and lipase levels were slightly elevated.
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