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As autophagy controls both the function and numbers of cellular organelles including mitochondria, we addressed the question of whether or not autophagy activation upon mortalin knockdown would lead to an elevated level of specific mitochondrial clearance called mitophagy.
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On the other hand, the allosteric ligand binding sites that developed during evolution by mutations in the C-terminus enable fine-tuning of the regulatory enzyme by the elevated levels of specific downstream metabolites.
On the other hand, the allosteric ligand binding sites that developed because of mutations in the C-terminal region enable fine-tuning of the regulatory enzyme in response to elevated levels of specific downstream metabolites.
Previous studies using a small number of patients with HPS and methylation specific PCR (MSP) have identified elevated levels of specific promoter methylation in both polyps and normal mucosa relative to non-diseased mucosa from subjects with sporadic serrated polyps [6].
While elevated levels of specific MMPs have been found in the serum of SLE, MMPs are less well characterized in CLE.
If confirmed by other studies, these elevated levels of specific antibodies may be a useful predictor or biomarker of AMD progression from intermediate to late AMD.
ABPV-infected bees produced neither elevated levels of specific antimicrobial peptides (AMPs), such as hymenoptaecin and defensin, nor any general antimicrobial activity, as revealed by inhibition-zone assays.
It was demonstrated that CMA patients are characterized by elevated levels of specific IgE levels as well as the specific IgG levels (Shek et al. 2005; Meulenbroek et al. 2013).
After IEAgs immunization of guinea pigs, the present study successfully produced ASHL animals with elevated levels of specific antibodies in their serum; that is, an ASHL animal model was obtained.
Recent studies have reported elevated levels of specific cytokines in gingival overgrowth tissue, particularly TGF-beta, suggesting that this growth factor plays a role in the accumulation of extracellular matrix materials.
ABPV-infected individuals did not produce elevated levels of specific AMPs such as hymenoptaecin, and we did not detect any general antimicrobial activity in the inhibition-zone assay (Fig. 4).
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CEO of Professional Science Editing for Scientists @ prosciediting.com