Sentence examples for elevated in osteosarcoma from inspiring English sources
Serum alkaline phosphatase (SALP) is commonly elevated in osteosarcoma patients.
Our results indicated that Stat3 phosphorylation levels were elevated in osteosarcoma, rhabdomyosarcoma and other soft-tissue sarcoma tissues and cell lines.
RUNX2 encodes a master transcription regulator of bone development and osteoblast maturation (reviewed in Komori, 2010), and is shown to be highly elevated in osteosarcoma tumours (reviewed in Martin et al, 2011).
We demonstrated that the levels of Stat3 phosphorylation is elevated in human osteosarcomas, rhabdomyosarcomas and other soft-tissue sarcomas tissues.
Stat3 phosphorylation is elevated in human rhabdomyosarcoma, osteosarcomas, and other soft-tissue sarcomas.
This study demonstrates that Stat3 phosphorylation is elevated in human rhabdomyosarcoma, osteosarcomas and soft-tissue sarcomas.
As shown in Figure 1, Osteocalcin expression is elevated both in osteosarcoma patients and in healthy haemopoietic stem cell donors, without any significant difference between the two groups.
Cell viability was determined by MTT assays and induction of apoptosis was analyzed by western blotting using antibodies that specifically recognize cleaved caspases-3, 8, and 9. Stat3 phosphorylation is elevated in 19% (21/113) of osteosarcoma, 27% (17/64) of rhabdomyosarcoma, and 15% (22/151) of other soft-tissue sarcoma tissues as well as in sarcoma cell lines.
PTH was elevated in 7.6%.
In normal osteoblasts, RUNX2 mRNA and protein levels are elevated in quiescent cells upon growth factor deprivation [ 23, 41], but this growth-related regulation of RUNX2 gene expression is perturbed in several osteosarcoma cell types that express RUNX2 at elevated levels [ 23- 26].
The gene amplification, elevated protein expression, and lack of association with clinical characteristics or prognosis indicate that RUNX2 gene amplification and protein overexpression might be early events in osteosarcoma pathogenesis [6], [32].
