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Generally, the decline in fruit firmness due to softening is accompanied by elevated expression of numerous cell metabolism enzymes, including polygalacturonase (PG) [ 5, 6], pectin methylesterase (PME) [ 7], β-galactosidase [ 8], as well as cell wall loosening proteins such as expansin [ 9, 10].
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Elevated expression of SPARC has been reported in numerous animal models of fibrotic diseases and human fibrotic tissues [ 19].
Elevated expression of focal adhesion kinase (FAK) occurs in numerous human cancers including colon-, cervix- and breast cancer.
Gene expression analysis revealed elevated expression of JunD, a downstream target of JNK, in P38α−/− erythroblasts.
Gene expression profiling did not reveal elevated expression of other members of the P38 kinase family (P38β/γ/δ) in P38α−/− erythroblasts.
Moreover, elevated expression of GNA13 promoted colorectal cancer metastasis by triggering the epithelial-mesenchymal transition (EMT 27.
Amplification and elevated expression of c-myc in a chemically induced mouse colon tumor.
Elevated expression of Rab25 has been seen in this malignancy.
Significantly elevated expression of both Arc and H1a was observed.
Elevated expression of MNK2a, a result of alternative splicing of MKNK2, is known to activate the p38-MAPK stress pathway43.
Elevated expression of protein spots 1 6 in the serum of ovarian cancer patients compared to serum from healthy volunteers.
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