Given there was no correlation between skin rashes and clinical hepatitis or elevated aminotransferase, these two entities of adverse events may need different approaches for monitoring and management.
IgG4-related disease (IgG4-RD) is a new disease entity characterised by elevated serum IgG4 concentration and/or tissue infiltration by IgG4-positive cells.
IgG4-related disease is a novel disease entity characterized by elevated serum IgG4 and tissue infiltration by IgG4-positive plasma cells.
Some adhesion molecules, such as L1, however show elevated expression in some tumor entities.
Further investigations are needed to study the effects of selective renal denervation in other entities linked by elevated sympathetic activity.
Second, and in contrast to reports from other cancer entities, we observed that elevated BTG2 expression levels in bladder cancers were linked to a strongly decreased cancer-specific survival.
Moreover, the legally elevated status of the fetus as an individual entity, separate from the mother, has resulted in focussing public attention on the behaviours of pregnant women and heightened the vigilance expected of them [ 24].
Studies investigating cause-specific mortality, be it mainly mortality from cardiovascular reasons, cancer or other disease entities, may further elucidate the relationship between elevated resting heart rate and longevity.
The ALERT algorithm may prove to be especially useful for entities that need to define a programmatic "elevated respiratory illness season" (eg, a health system, hospital, or a clinical trial).
Other interesting enriched biologic entities among the set of genes with elevated expression (Additional file 8) were the interrelated WNT signaling pathway, cell adhesion, and calcium binding (Additional file 9).
In the independent validation RT-qPCR data, where we picked samples from all histological entities, the papillary carcinomas again show a distinctly elevated expression of SERPINA1 compared to all other histological groups under investigation.
