Sentence examples for elevated apoptosis associated from inspiring English sources

Manipulating the MSCs to secrete SFRP2 caused reduced proliferation and elevated apoptosis associated with increased necrosis within the tumors.

From these observations, we propose a novel mechanism of cellular radiation hypersensitivity, whereby abnormally high expression of artemis may act as a dominant negative resulting in increased DNA DSB and elevated apoptosis associated with clinical and cellular radiosensitivity.

Collectively, these studies identified the c-Myc-imposed reduction in p21Waf1/Cip1 levels as an important factor determining the increased sensitivity to camptothecin-induced apoptosis associated with elevated c-Myc levels.

Further, we found that telomerase-mediated resistance to apoptosis was jnk-dependent because apoptosis associated with ectopic expression of hTERT resulted in elevated levels of p-jnk while suppression of jnk expression by jip abolished resistance to apoptosis.

The apoptosis associated protein caspase-3 was also increased after cytomix addition.

By contrast, 2DG depleted ATP levels more than lonidamine and had a slower onset of PDT cytotoxicity, beginning around 4 h after PDT, which was probably necrotic, as it was not associated with elevated apoptosis.

However, overexpression has also resulted in a loss of cell viability, associated with increased DNA damage and elevated apoptosis as a result of abnormal activity of the artemis endonuclease inducing DNA breaks (Multhaup et al, 2010).

Overexpression of the artemis protein in these cells was associated with reduced cell survival, increased DNA damage and elevated apoptosis.

(3) Basal cells physically associated with these immune cells generally displayed distinct signs of degeneration, including substantially elevated apoptosis, necrosis, and reduced tumor suppressor p63 expression.

Results revealed that bacteraemia was accompanied by elevated apoptosis.

We next sought to determine whether enhanced apoptosis was associated with elevated levels of ASK1, a common mediator of apoptosis.