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In response to low oxygen supply, cancer cells elevate production of HIF-1 α, a hypoxia-inducible transcription factor that subsequently acts to stimulate blood vessel formation and promote survival.
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If the elevated fat storage in GSC animals reflects simply elevated production and storage of 'good' lipids, we might expect skn-1 to support this fat production.
Interleukin-6 aborts lymphopoiesis and elevates production of myeloid cells in systemic lupus erythematosus-prone B6.Sle1.Yaa animals.
Jung, W. S., Kang, J. H., Chu, H. S., Choi, I. S. & Cho, K. M. Elevated production of 3-hydroxypropionic acid by metabolic engineering of the glycerol metabolism in Escherichia coli.
Adoptive transfer of Ddit3 null CD8+ T cells induced a higher antitumor effect, compared to that triggered by Pmel controls (Fig. 6b), which correlated with a higher frequency of the transferred Pmel T cells expressing IFNγ in tumors and elevated production of IFNγ after challenging of splenocytes with gp10025 33 peptide (Fig. 6c, d).
2. Lukaszewicz, A.-C., Gontier, G., Faivre, V., Ouanounou, I. & Payen, D. Elevated production of radical oxygen species by polymorphonuclear neutrophils in cerebrospinal fluid infection.
In mitochondria, MDA has an inhibitory effect on mitochondrial complex I- and complex II-linked respiration and significantly elevates production of reactive oxygen species and protein carbonyls [ 44].
This view is consistent with the previous results in the spontaneously hypertensive rat (SHR) which has elevated production of 20-HETE and preglomerular vascular resistance, and is protected from hypertension-induced renal end-organ damage [ 1, 18].
Immune system of a subgroup of ASDs is triggered by gluten and casein; this could be related either to AGA, DPG, and Casein IgG elevated production or to impaired intestinal barrier function.
Another MLS-biased miRNA, bmo-miR-278, walsolso found at MLS, and its homolog dme-miR-278 was proven to control energy homeostasis in Drosophila, since miR-278 mutants have elevated insulin production and elevated circulating sugar [77].
Intensified efforts have been carried out to elevate artemisinin production.
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