Sentence examples for elements to mediate from inspiring English sources

Either MAEBL serves simply as an adhesin to mediate sporozoite attachment to the salivary glands or the C-terminal portion of MAEBL also has a role to interact with cytoplasmic elements to mediate its function during invasion.

At least 15% of human disease-causing mutations occur at splice sites [ 16]; mutations and genetic variations can alter the splice site signals and splice regulatory elements to mediate formation of alternate transcripts and protein isoforms [ 17- 20].

As ERα and PR may interact on progesterone response elements to mediate transcriptional activation [ 56], we next assessed overlap between our previously published ERα cistrome in ZR-75-1 cells [ 31] with the estrogen pretreated PR cistrome generated here.

A deleterious effect of nLTR-RT related to the length of the elements has previously been described in Drosophila and in humans (Boissinot et al. 2001, 2006; Petrov et al. 2003, 2011) and results from the greater ability of long elements to mediate ectopic recombination events, which are extremely deleterious (Langley et al. 1988; Song and Boissinot 2007).

Biological data indicate that the number of transposable elements scales with genome size (Oliver et al. 2007), and in Arabidopsis the reduction of genome size could be linked to the capacity of one family of transposable elements to mediate rearrangements (Devos et al. 2002).

Results of gel-shift assay demonstrated that other protein(s) might also be involved in interacting the E4 element to mediate the negative effect of estradiol on the hGnRH upstream promoter activity in JEG-3 cells.

To generate a potent reversible EMT-inducing stimulus, we created a Snail-1 retroviral expression construct using a fused estrogen receptor (ER) response element to mediate regulation by exogenous 4-hydroxy-tamoxifen (4-OHT).

The TFII-I is a multifunctional transcriptional factor known to bind specifically to several DNA sequence elements and to mediate growth factor signalling.

This promoter region was chosen since the light responsive element of the per2 gene was found within this region [25], and also the AP1 elements suggested to mediate light responsiveness of the cry1a and wee1 genes are located within these boundaries [24].

DNA elements known to mediate such responses were also identified in our SynE collection.

The intervention is aligned with Australian [ 75] and international [ 76] policy directions regarding the key elements thought to mediate high quality person-centred dementia and palliative care.