Sentence examples for elements to induce from inspiring English sources

In conditions of oxidant stress, the transcription factor Nrf2 binds to antioxidant response elements to induce expression of both phase I (acute) and phase II (late-stage) detoxifying enzymes.

AONs can be designed against splice sites or enhancer elements to induce exon skipping in cells of DMD patients, and have shown restoration of the reading frame of dystrophin 28 days after intramuscular injection of AON into the tibialis anterior muscle [16].

We'd been thinking about using transposable elements to induce cancer in mice.

Once activated, STAT3 forms homodimers, translocate to the cell nucleus and binds to specific regulatory DNA elements to induce transcription.

Both the low dose of STZ and the high fat diet are essential elements to induce type 2 diabetes with insulin resistance.

To test this proposition, we expanded the vascular Hoxc11 expression domain normally restricted to the lower limbs by utilizing an innovative integrated tetracycline regulatory system and Transgelin promoter elements to induce Hoxc11 expression universally in VSMCs of transgenic mice.

The name Mutator originates from the ability of active copies of this element to induce mutations corresponding to diverse recombination events, which were first described in plants (Bennetzen 1984; Jiang et al. 2011) and later in other organisms (Amyotte et al. 2012).

This dimer recognizes the hypoxia response elements (HREs) to induce target gene expression.

The HIF complex binds to the promoter hypoxia response elements (HREs) to induce the expression of target genes that regulate the cellular adaptive response to low oxygen tension [ 3, 4].

In an autocrine fashion, 1α-OHase activates 25(OH D which binds to VDRs and then vitamin D response elements (VDRE) to induce genes for the AMPs, β defensin 4A and hCAP18.

Typically, steroids enter the cell by passive diffusion and bind to cognate intracellular receptors to cause activation and an increased residency of the receptor steroid complex in the nucleus, where the complex binds to DNA at biologically active hormone response elements (HREs) to induce or repress gene transcription.