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While numerous studies have investigated regulation of expression level, little is known about gene design elements that govern expression costs.
Since the early 1990s, scientists have managed to identify naturally occurring molecules that control energy expenditure, satiation, and other elements that govern weight gain and loss.
The cytokine responses characterizing the inflammatory bowel diseases are the key pathophysiologic elements that govern the initiation, evolution, and, ultimately, the resolution of these forms of inflammation.
In the last period, with the help of X-ray crystallography, much progress has been achieved for the drug-design of selective CA IX inhibitors, by considering the three main structural elements that govern both potency and selectivity, that is, a zinc binding group (ZBG), an organic scaffold, and one or more side chains substituting the scaffold.
These sequences are putative SP1 transcription factor binding sites that may represent important cis-acting DNA regulatory elements that govern the expression of Cox-2.
The 3'-untranslated regions (UTRs) often contain regulatory elements that govern spatial and temporal properties of mRNAs, including mRNA stability, localization and translation [17].
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DNA sequences of both coding regions and non-coding regions which harbor cis-elements that govern expression, are phylogenetically conserved [ 14- 16].
The finite element equations that govern the time response of the actuators are provided.
Past studies on understanding the relationship between transcriptional regulation and immune function have largely focused on characterizing the regulatory elements and transcription factors that govern their transcription.
Microtubules (MTs) are the fundamental structural elements of all cells that govern a myriad of cellular functions, including motility, maintenance of cell morphology, intracellular transport, mitosis and meiosis.
Additional knowledge of genomic variation segregating within and among populations with known ecologies, of regulatory elements and the networks that govern gene expressions under both neutral and adaptive evolution reveals the importance of alternative signatures to the functional attributes of DNA elements.
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