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Residuals are thought as elements of variation unexplained by the fitted model and then it is expected that they occur according to a normal distribution (Meski et al. 2011).
In the search for such specific factors of the anthocyanin methylation process, the key was to find elements of variation that were significantly independent of the global anthocyanin VvMybA cis-regulated channel.
Although many other elements of variation may be involved in anthocyanin methylation, we may hypothesize a model as follows: VvAOMT1 is the fundamental isogene for anthocyanin methylation under strict functional constraint, while VvAOMT2 undergoing lesser functional constraint is responsible for fine and specific differences in the level of methylated anthocyanins (see proposed model Figure 6).
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However, there are elements of variations from country to country.
Here, we focus on one such element of variation: methylation of lysine 4 in histone H3 (H3K4).
More importantly, the degree of methylation in vitro had a profound effect on the transformation efficiency introducing an element of variation in the method.
Although difficulties regarding the reproducibility of grade of DCIS between pathologists have been described (Ellis et al, 2006), in the present review, all cases were examined by one pathologist, reducing this element of variation.
Although this psychological process does not appear new in psychology with regard to a patient's adjustment and coping to health diagnosis, 26 27 this study contributed to explore its consistency and element of variation in the case of caregivers, and in particular when a rare disease is concerned.
Here, we can only note that twice removing the solar element of variations in foF2 (using the regression method and the 11-year running mean) provides a weaker foF2 trend than that obtained using only the 11-year smoothing.
In this analysis we did not examine copy number variation at the level of individual genes or specific genetic elements, but instead focused on documenting the larger elements of structural variation that cover approximately 20 kb and more.
Nonetheless, a similar method of analysis to ours has been applied in previous studies and provides an indicator of some of the elements of the variation in cephalothorax color e.g. [60].
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