Sentence examples for elements of target from inspiring English sources

Free FRα translocates into the nucleus where it binds to cis-regulatory elements of target genes and directly activates transcription.

Indeed, fine particles should soar above hot surface and the presence of nanoparticles with enormously varying mass values provides the most efficient use of thermal energy to break bonds between nanoscopic structural elements of target material.

For example, RAS method should be assigned to the first group because of its multiplicative pattern (3), whereas Kuroda's method belongs to the second group because it does not include any mechanisms for fitting the proper elements of target matrix to required zero level.

In the case of PPARβ/δ [25], as with other PPARs, the genomic pathway is thought to involve binding to retinoid X receptor (RXR) and the formation of heterodimers which then bind to response elements of target genes.

Biochemical studies have demonstrated that Twist1 and Hand1/2 formed hetero-dimers or homo-dimer with E12, E47 and between themselves to activate or suppress transcription of downstream target genes through binding E-box sequences such as the degenerate Thing1-box, CGTCTG, in the cis-regulatory elements of target genes [1], [6], [9], [10], [11].

Once activated by a ligand, the receptors bind to the promoter elements of target genes.

Signature strikes are one of the most controversial elements of targeted killing operations begun duringGeorge W. Bush's presidency and embraced and expanded byPresident Obama.

Yeast one-hybrid screening is a powerful tool for the identification and isolation more transcription factors using promoter segments or regulatory elements of targets as baits.

Therefore, the predicted forward ligation of the donor into the targeted locus retains the original reading frame and both 5′ and 3′ regulatory elements of targeted genes.

However, the coding sequence of targeted endogenous genes was disrupted or the expression pattern of inserted exogenous genes could not well recapitulate the endogenous ones as insertion occurred within either the exon or cis-regulatory elements of targeted genes.

Here, using the CRISPR/Cas9 system, we developed an intron targeting-mediated and HR-independent efficient knockin approach for zebrafish, with which the intactness of the coding sequence and regulatory elements of targeted endogenous genes are maintained.