Sentence examples for elements of signalling from inspiring English sources

This was not an unexpected result, as many key regulatory elements of signalling pathways in mammalian cells are regulated by non-transcriptional controls [34], [35], and so do not appear as DE genes within microarray datasets.

Molecular components involved include integrins, elements of signalling machineries, soluble and membrane-bound proteases (including matrix metalloproteases, or MMPs), and prominently actin and actin-associated proteins such as e.g. cortactin [ 14- 18].

Through comparisons and combination of the goldfish olfactory epithelium ESTs produced in this study with those available for zebrafish it was possible to estimate that the olfactory epithelium transcriptome contain around 16,400 unigenes and to identify a number of nervous tissue markers and several elements of signalling pathways involved in olfaction.

As elements of signaling pathways, second messengers can serve to integrate information when multiple independent upstream inputs influence the rates of synthesis and degradation of the second messenger.

The adenylyl cyclases (ACs) are a family of enzymes that are key elements of signal transduction by virtue of their ability to convert ATP to cAMP.

Therefore, we also assessed the native signal peptide of AT (NTss) even though the structural elements of signal peptides from extracellular proteins are different between S. aureus and E. coli.

Permanent excitation of nerve cells due to the absence of negative regulation is another example of the impact of xenobiotics on one or several control elements of signal transduction.

Due to the fact that topologically interesting nodes tend to represent key regulatory elements of signaling cascades, while differentially expressed genes are likely to be found among target genes whose expression is regulated by these cascades, a combined analysis could provide new insights in the molecular mechanisms underlying the antioxidant activity of small molecules.

A large proportion of these 61 genes encode receptors, transporters, transcription factors and elements of signal transduction.

This network includes elements of signaling pathways associated with early development, including canonical Notch, Wingless, Epidermal Growth Factor, and Hedgehog signaling pathways.

Therefore it allows identification of many important elements of signal transduction pathways which themselves do not come up as differentially expressed genes or proteins.