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Dorsal and Twist bind to closely linked DNA elements in a number of promoters and synergistically activate transcription.
This assay has been instrumental for the identification of active regulatory elements in a number of human cell lines by ENCODE [ 26].
Moreover, it has become increasingly clear that miRNAs are integral elements in a number of crucial gene expression networks, acting in tightly regulated feedback loops that are often disrupted in cancer.
HIF-1α combines with HIF-1β to form the fully functional transcription factor, which is capable of binding to cis-acting regulatory elements in a number of hypoxia-responsive genes, including the gene for EPO.
Since the first report of the methods for quantitative analysis, chemically specific fluorescence imaging has been employed to follow chemical localizations of trace elements in a number of biological and environmental systems.
The shadow enhancers consisting of transcription factor binding site tandems, usually degenerative, were described as important cis-regulatory elements in a number of developmental genes in animals [ 44- 46].
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Joe Gunther, the raw-boned Vermont detective in these rugged novels, finds the common element in a number of recent burglaries: all the jewelry and objets d'art seem to be finding their way to Northampton, Mass., an old manufacturing town that's been retooled as an upscale art center.
A recurring element in a number of the much-admired, widely circulated cartoons about Modern art that Reinhardt published is a drawing of a mocking businessman who laughs in the face of an abstract painting and demands to know what, exactly, it's supposed to represent.
This enzyme has also been identified as a key element in a number of pathways known to be frequently activated in neoplastic processes and which give tumor cells a survival advantage when compared to healthy cells.
The striated appearance closely resembles the ultrastructures formed upon heterologous expression of SYCP3 in vivo (Yuan et al., 1998) and the SC lateral element in a number of species (Westergaard and von Wettstein, 1972).
Magnesium (Mg) is an essential element in a number of biological processes [ 1, 2]; however, in patients with chronic kidney disease who require dialysis, balance in serum and total body Mg can be easily disturbed by poor dietary intake [ 3] or impaired regulation of Mg in the kidney, leading to a number of adverse conditions.
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