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Heterogeneous targets need adaptive drug molecules, characterised by the presence of flexible elements at specific locations that sustain a viable binding affinity against existing or expected polymorphisms.
The process of neurite formation requires the assembly of cytoskeletal elements at specific membrane sites.
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The variability of the current intensity and the complicated morphology of the corresponding whorl and its latitudinal or local time displacements with respect to a given observatory location give rise to different patterns of the daily variation of the geomagnetic elements at that specific observatory (Mayaud, 1965).
Number of repeated BRE elements at the specific locus.
However, we cannot exclude the possibility that trace-element accumulation at specific localized sites, eg, bone-mineralization fronts or within osteoblasts, causes problems, nor can we exclude the possibility that the causes of fracture differ among patients.
Are core promoter elements at tissue-specific genes designed to recognise variant TAFs?
Different strains of S. aureus can exhibit important differences in gene content owing to the presence/absence of plasmids and/or mobile elements integrated into the chromosome [e.g., staphylococcal cassette chromosome (SSC) elements, prophage], usually at specific loci termed "genomic islands" [ 27].
A Ziploc bag must be used to prevent trace elements of radiation at specific sites from contaminating the counter itself.
Actually, there's a further arbitrary element at work, specific to Terry Pratchett, when he wins a prize for children's books.
CNVs involve an increase or decrease in the number of copies of a repeat element at a specific genomic location.
Within a population of a bacterial species, the variation in the number of copies of the repeat element at a specific locus indicates the diversity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com