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Any of these circuits represent a potential elementary functionality triggered by the corresponding signal output node.
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The aim of the method proposed here is focusing on the actual elementary functionalities triggered by these circuits within the context of the pathway, whose failure (wrong activation state, tested by the method) can be associated to the disease.
Unlike prior approaches that distribute the ETL only at coarse-grained level of processing, our approach provides different ways of parallelization/distribution both at process, functionality and elementary functions levels.
The novel approach allows thereby the distribution of the ETL process at three levels: the "process" level for coarse-grained distribution and the "functionality" and "elementary functions" levels for fine-grained distribution.
Elementary functions.
It is shown that the MCSs can be computed from the set of target modes, which comprises all elementary modes that exhibit the functionality to be attacked.
It is additionally shown that the other way around is also possible: the elementary modes belonging to a certain functionality can be computed from the respective set of MCSs.
Elementary flux mode (EFM) analysis, a powerful tool to analyze the functionality of metabolic networks from their topology [ 30], and FBA simulations, were carried out.
It means that Apple has patented something with is fairly elementary and obvious and is doing it so that it might add this functionality later — or not.
Thus, weighted sum of fluxes through these elementary modes for each reaction, called control-effective fluxes (CEF), lead to the implicit incorporation of functionality and regulation into metabolic network structures [ 11, 13, 14].
Each elementary step of the reaction must be compatible with water and the large excess of nucleophilic functionalities found in Nature (e.g., amines, thiols, hydroxy groups).
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