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The CHC-AuNR nanoprobe was evaluated in simulated urine solution and a LDL as low as 1.5 pM was achieved at an estimated AuNR/CHC ratio of 2. Elemental mapping and protein adsorption kinetics over three orders of magnitude in HSA concentration confirmed accumulation of HSA on the nanorods and revealed the adsorption to be completed within 15 min for all investigated concentrations.
We used FlyAtlas to analyse protein elemental content with respect to protein expression in various tissues of D. melanogaster (see Table 3 for tissues).
Enteral nutritional feeding with elemental or whole protein feed is often used as either primary or adjuvant therapy for Crohn's disease.
However, it has also been suggested that, at least for sulfur, the elemental makeup of proteins is correlated with the chemical compositions of the environment [4].
"Stoichioproteomics" relates the elemental composition of proteins and proteomes to variation in the physiological and ecological environment.
Comparative analyses of molecular-scale variations in the elemental compositions of proteins among plant and animal species are currently very scarce (see e.g. [ 2, 9]).
In first studies they performed elemental labelling of proteins (lysozyme and BSA) with Eu, Tb and Ho-SCN-Bn-DOTA and separated them via SDS-PAGE followed by LA-ICP-MS detection [21].
Protein hydrolysates constitute an alternative to intact proteins and elemental formulas in the development of special formulations designed to provide nutritional support to patients with different needs.
Mulder carried out elemental analysis of common proteins and found that nearly all proteins had the same empirical formula, C400H620N100O120P1S1.
A general elemental composition for recombinant protein was taken from [ 3].
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