Sentence examples for element which binds from inspiring English sources

Each mRNA sequence starts with a cis-regulatory element which is used as binding site that regulates the activation of the protein, followed by a parameter sequence, which in turn is followed by a trans-acting element which binds to other cis-regulatory elements to control their expression and activation; all represent the translated protein.

However, nearly all of the binding energy was contributed by the IST1 MIM1 element, which bound ULK3 MIT2.

Electrophoretic mobility shift assays and functional studies using PathDetect systems show that stimulation of the cells by phorbol esters leads to activation of the Elk1 transcription factor, which binds to its element in the 9E3 promoter.

NRF2 is a transcription factor which binds to the antioxidant response element in the promoter of NRF2 regulated genes [32].

We introduce the concept of dualsteric ligands that consist of distinct elements which bind to each of the orthosteric and an allosteric domain on a single receptor to enhance subtype selectivity.

Multiple ACGT motifs have been shown to form enhancer elements which bind synergistically to transcription factors for gene regulation [ 40].

To date, many PRC1 target genes have been identified including homeobox (HOX) genes and p16 INK4a, whose promoters contain interactive elements which bind directly to Bmi1[ 12].

Wild-type but not mutant p53 bound strongly to a conserved element in the GADD45 gene, and a p53-containing nuclear factor, which bound this element, was detected in extracts from irradiated cells.

The transcriptional activation of calpain involves the promoter/enhancer motif, 12-o-tetradecanoyl-phorbol-13-acetate response element (TRE), which binds AP-1 [44], [44], a dimer consisting of c-fos and c-jun [45].

cAMP-activated protein kinase A phosphorylates the cAMP response element binding protein (CREB), which binds cAMP responsive element (CRE) cis-regulatory elements in the Aanat promoter and induces transcription [ 32, 33].

Both promoter regions of DDAH-1 and DDAH-2 contain a sterol response element which could bind the statin-induced transcription factor sterol response element binding protein (SREBP).