Proliferation of IS elements in the evolutionary past of A. asiaticus might thus have been an important process during the adaptation of A. asiaticus to an intracellular life style in which its genome was shaped by their activity.
In other words, it is not simply a matter of weak purifying selection allowing active spread of the elements, but an effect of the element mutational dynamics introducing directional bias in the evolutionary process.
This pattern likely reflects the general incorporation of additional caudal vertebral elements during the evolutionary increase in style size.
A single event of anomalous packaging of an improperly spliced subgenomic RNA, followed by reverse transcription could lead to an env-less element in an evolutionary blink of an eye.
The cumulative acquisition of these, but probably many more, genetic elements by E. faecium has resulted in the evolutionary development of a genetically distinct E. faecium subpopulation with a progressively increasing fitness in hospitalized patients (Willems et al. 2011).
This variant is located in the evolutionary conserved PRE-element 5′ upstream of the FSHB gene transcription site, a regulatory element demonstrated to be functionally active in controlling mammalian FSHB expression (Webster et al., 1995).
When that is honored, the exchange of information among self-aware constituencies within localized and distant tissue ecologies becomes the crucial element in an alternative evolutionary framework pertinent to cancer dynamics in which both are viewed as an uninterrupted cellular problem-solving process at every scope and scale in repeated reaction to environmental and epigenetic stresses [11 14].
There was no congruence between the trees generated in this study based on TEs and proposed phylogenetic hypothesis for the group, suggesting that horizontal transfer, emergence or elimination of specific TE lineages, could have had important effects in the evolutionary history of Rex elements in the cichlid genomes.
These similarities in the evolutionary patterns of these elements suggest a strong association.
