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We have also shown that these correlations are related to the functional deformation modes of this secondary structure element, derived from the geometry of the β-sheets and from the requirement of maintaining inter-strand hydrogen bonds.
One strategy for potentially diminishing vector insertional mutagenesis is through the use of self-inactivating lentiviral vectors containing the 1.2-kb insulator element derived from the chicken β-globin locus.
To investigate the biochemical basis for the distinct functions of Sox2 and Sox17, we solved the crystal structure of the high mobility group domain of Sox17 bound to a DNA element derived from the Lama1 enhancer using crystals diffracting to 2.7 Å resolution.
A DNA element derived from the pOPI3CAT expression vector containing three symmetric lac operator (lacO) binding sites recognized by the lac repressor (lacI), within a SV40-derived intron, was subcloned between the transcription start site of the endogenous Vav-gene and the multiple cloning site (MCS) of the HS21/45 VavP-transgenic vector.
It binds to and activates transcription from the HIF-1 α response element derived from the 3-prime flanking region of the EPO gene.
This cell line was stably transfected with the luciferase reporter gene and estrogen-responsive element derived from the Xenopus vitellogenin A2 gene.
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The incestuous element derives from the fact a decent proportion of R&A members will also be attached to Muirfield.
The Azerbaijani are of mixed ethnic origin, the oldest element deriving from the indigenous population of eastern Transcaucasia and possibly from the Medians of northern Persia.
The MNO/PNO element derives from the assumption that if different siRNAs produced by a clone insert match sequences within the target transcript, then there will be a greater chance of the target transcript being knocked down compared with when siRNAs produced from a single region of a clone insert match only one or a few sequences within the target transcript.
In addition, there are skeletal elements derived from the gill arches of primitive vertebrates, collectively termed the visceral skeleton.
Helixhunter's results can in turn be used to probe a library of secondary structure elements derived from the structures in the Protein Data Bank (PDB).
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