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(B) Electrostatic surface potential of EBOV NPcore.
(A) The electrostatic surface representations showing the tunnel for RNA binding.
Open image in new window Figure 6 Electrostatic surface interpretation ofSeADO structures.
Molecular modeling and electrostatic surface area were determined to explain the activities of the analogs.
The electrostatic surface potentials are finally taken into account to evaluate stability.
Open image in new window Figure 4 Electrostatic surface features relevant to the cleft for substrate binding.
Rendering of a molecular orbital isosurface (left) and an electrostatic surface potential mapped onto the electron density (right).
(B) The BubR1 KARD domain structure (in sticks) is laid on top of electrostatic surface representation of B56γ1.
The electrostatic surface potential of EBOV NPcore was calculated using APBS tools, with limits ±5 kbT/ec.
Open image in new window Figure 2 Comparison of the electrostatic surface potential of hFAN1 and PaFAN1.
The LGI1 structural model has been evaluated for both conserved regions and electrostatic surface (Figure 6).
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