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(C D ) Close-up views of the hydrophobic interface between α2/3i and α3i+1 and the electrostatic interface between α1i and α2/3i+1.
Supporting the importance of this interface in v-Fps, the AX9m mutation in v-Fps inserts a LE dipeptide between E832 and L833 in the SH2 αA helix, which likely disturbs the electrostatic interface between the SH2 domain and kinase αC helix.
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These tertiary structure similarities between PYRIN and CARD domains indicate that like for CARD-CARD interactions, an electrostatic interface may play an important role for the biochemical properties and the interaction behavior of PYD-containing molecules [36], [37].
The hydrophobic protein interface is shown in black dash-line and the electrostatic interface in grey dash-dot line.
The E26R and R64C mutants, both mapped to the electrostatic interface for mediating MAVS oligomerization, were chosen for structure determination.
It argues strongly that the filament formation through the electrostatic interface is critically correlated with the MAVS signaling (interferon production).
Electrostatic interfaces – systems that make your fingers "feel" textures on a smooth metal plate – have been around for a long time.
The unfolding was initiated by the breaking of electrostatic interactions at the interface between 3′➔5′ exonuclease and 5′➔3′ polymerase domains.
Similarly, there is no need to know the electrostatic energy across the interface between a gas phase and the interior of a condensed phase.
Finally, the electronic, or electrostatic, attraction theory suggests that electrostatic forces develop at an interface between materials with differing electronic band structures.
The former relies on electrostatic charge storage at the interface between electrode and electrolyte, which are usually composed of carbon based materials.
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