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However, exploring the whole phase diagram with such a large number of charges would be unfeasible, because of the computationally overwhelming number of electrostatic interacting pairs to be evaluated.
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Mutation of these lysines completely abrogated the effect of the helix on mitochondrial bioenergetics, suggesting that αH6 required electrostatic interactions to interact with mitochondria (Figure 2C).
These results are consistent with recent evidence that many proteins that bind to PI 4,5 P2 through an electrostatic interaction also interact redundantly with PI(4 P in the membrane [ 27].
In sum, the V-domains of almost all functional K+ channels possess conserved charged residues that are available to interact via electrostatic interactions (Fig. 6) [54].
GdnHCl interacts via electrostatic interactions due to its ionic properties; however, urea operates through chaotrophic effects [ 30].
Polymeric nanofibers as sensors are made from a carbon nanotube (plastic)/cement composite and utilize electrostatic interactions between molecules to interact with their surroundings.
In particular, a single lysine residue appears to provide the critical minimum charged surface required for interacting with heparin through electrostatic interaction and simultaneously plays an unrelated yet critical role in the liver tropism of AAV6 vectors.
The interaction of charybdotoxin with membranes is heavily influenced by electrostatic interactions, suggesting that the toxin interacts relatively superficially, similar to what we observed with PcTx1.
In particular, αH6 interacts with mitochondria through electrostatic interactions involving the lysines 157 and 158 and immediately induces an inhibition of state-3 respiration and a slight uncoupling of state-4 respiration.
In particular, αH6 interacts with mitochondria through electrostatic interactions involving the lysines 157 and 158 and induces an inhibition of state-3 respiration and an uncoupling of state-4 respiration.
The calculated results indicated that c RGDfK) interacted with αvβ3 mainly by electrostatic interaction, stabilization interaction, and hydrophobic interaction.
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