Your English writing platform
Discover LudwigExact(2)
To monitor adherence, study drugs were dispensed to the participants in a bottle with an electronic cap that recorded each pill bottle opening using the Medication Event Monitoring System (MEMS) (Aardex. (2004), Union City, CA).
A similar study among adolescents receiving ART at the Joint Clinical Research Centre in Kampala, Uganda, found that 93, 67 and 23%% of patients had an adherence of greater than 95%% as measured by self-report, clinic based pill counts and electronic cap methods, respectively [ 16].
Similar(58)
Patients recruited in the study were asked to return the electronic caps and the self-reporting form on each occasion of a visit to the IDCC.
In future studies, more robust measures of adherence could track actual medication use by recording the dates and times of medicine bottle opening with electronic caps.
This method has a close association with concurrent viral load [2], electronic pill cap adherence assessment [20], development of resistance [21], [22], and progression to AIDS [23].
electronic pill cap, which fits on a medication bottle and registers each time the patient's medication bottle is opened.
Self-report measures of ART adherence are often correlated with adherence estimates using more direct measures (e.g., electronic medication cap monitoring) and self-reported adherence is generally associated with HIV viral load (Simoni et al. 2006).
Patient adherence to prescribed therapies was determined at baseline and at 5 months, using both electronic pill cap monitoring (using the MEMS V Trackcap AARDEXX, Zug, Switzerland) and the Morisky Medication Adherence Scale (MMAS).
There was no statistically significant change in medication adherence based on electronic pill cap monitoring or the Morisky Medication Adherence Scale (MMAS); however, there was a trend towards improved adherence based on MMAS.
Significantly closer concordance has been observed between single-item global self-ratings of adherence and concurrently assessed adherence measured by electronic monitoring cap, compared with the concordance for self-report measures that focused on frequency of missed doses in HIV/AIDS (12).
To qualify for the intervention study and to receive an electronic bottle cap, participants were required to meet DSM-IV criteria for major depressive disorder (MDD) or dysthymia or to exhibit clinically significant depressive symptoms despite the prescription of an antidepressant.
Write better and faster with AI suggestions while staying true to your unique style.
Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com