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At more advanced stages of apoptosis, progression of chromatin compaction was associated with redistribution of chromatin fibres, resulting in electron-dense domains of degraded homogeneous-appearing chromatin.
After post staining with uranyl acetate and lead citrate, 100 nm thick retina sections observed by transmission electron microscopy revealed the characteristic appearance of rod nuclei which show a large electron dense HC domain located in their center (Figure 1B).
Their secretion is granular, but shows a characteristic structure with an inner, electron-dense area in a non-electron-dense oval structure (Fig. 7a, b).
In order to quantify the labelling density and its variations in the different nuclear domains, the primary antibody was immuno-gold labelled and the sections were observed by electron microscopy to determine the number of electron dense particles per surface area (Figure 3D F).
An electron dense plaque of ~100 nm [ 2] underlies the cytoplasmic domain of the tight junction.
In addition, small vesicles with electron dense materials were seen in transit within the tight junction membrane domain (Fig. 12B), suggesting that the tight junction might be an area of intercellular communication via targeted local secretion.
These intranuclear compartments were originally described by ultrastructure and differential electron density, and while the nucleus is now known to possess multiple domains or compartments, the nucleolus, nuclear envelope and differentiation between high and low electron dense hetero-and euchromatin clearly also applies to trypanosomes (Vickerman and Preston, 1970; Rout and Field, 2001).
The more electron dense membrane is thought to be postsynaptic.
Single QDs were detected by electron microscopy inside endocytic vesicles that become increasingly electron dense during maturation.
No electron dense deposit was identified.
Electron microscopy showed no electron dense deposits or organized deposits.
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