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Structural remodelling ultimately creates a substrate for AF due to electrical dissociation between muscle bundles and local conduction heterogeneities facilitating the initiation and perpetuation of AF.
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Although open-heart surgery was planned, he had a sudden cardiac death from an electrical-mechanical dissociation with no detectable cardiac output, probably related to occlusion of the tricuspid valve.
This was concluded from dissociation of electrical and hemodynamic data.
Stewart proposed that any compound, in solution, must satisfy both the principles of electrical neutrality and the respective dissociation constant, including water itself, where the dissociation constant (K'w) is equal to the product of hydrogen and hydroxyl ion concentrations ([H] × [OH]).
Therefore, modifications in the plasma ionic composition that jeopardize electrical balance drive adjustments in water dissociation in order to recover electrical neutrality and maintain the constancy of the ionic product for water, which ultimately alter the plasma concentration of hydrogen ions [ 1– 4].
The idea of ionic dissociation is used to explain electrical conductivity and many other properties of electrolytic solutions.
However, 30 years ago, Stewart proposed an alternative model of acid-base physiology based around the important observation that water has a dissociation constant and the principles of electrical neutrality [18].
To understand the influence of TiO2 layer thickness on the exciton dissociation efficiency, one needs to consider the electrical properties of the system.
They define PEA "as 'clinical absence of cardiac output despite electrical activity' and essentially an echocardiographic diagnosis…equivalent to electromechanical dissociation [EMD]." For all practical purposes, PEA is simply the absence of pulses despite the presence of electrical activity and is a clinical, not an echocardiographic, diagnosis.
"Dissociative fugue is the rare bird of dissociation, but dissociation as a phenomenon is very common," he said.
According to this approach, the dissociation equilibrium is supplemented with equations incorporating the necessity for electrical neutrality and the principles of conservation of mass.
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