Hubert B. Herring's critique of Westchester's ills [Soapbox, June 25] warrants the attention of all who are elected to further the best interests of the whole county.
We therefore elected to further investigate the potential of ATP-competitive mTOR inhibition in IPF by investigating the impact of such an approach on collagen synthesis in live precision-cut ex-vivo lung slices derived from transplant tissue from IPF patients.
Therefore, we elected to further characterise this novel region in detail, and its role in medulloblastoma.
Among the novel hits shown to affect AKT phosphorylation, we elected to further dissect the potential insulin signaling regulatory role of the previously uncharacterized protein PALD (KIAA1274, paladin).
We therefore elected to further test the relationship of podosome belts to resorptive behavior in osteoclasts, before using them as markers for this activity.
We therefore elected to further pursue the role of Cx43 regulation in mural cells.
It may be that their production of by apoptosing colorectal cancer cells within the liver contributes further to this process and it was elected to further test this hypothesis in vivo.
We and others have previously described a role for LRRK2 in regulating synaptic vesicle endocytosis and exocytosis and thus we elected to further explore the potential relationship between LRRK2 and Dnm1 (14, 24, 26).
Because of the potential regulatory implications of the presence or absence of effects at concentrations below the level of the current National Ambient Air Quality Standard (NAAQS) for O3 (currently 0.075 ppm) (NAAQS 2008), we elected to further examine the responses to 0.06 ppm O3 documented in the Adams (2006) study.
Thus, we elected to further investigate the nature of mutations in the 16S rRNA genes of SOPE along with (for context), its sister species, the primary endosymbiont of the maize weevil S. zeamais (SZPE), and the closely related insect symbiont So. glossinidius.
Following our interim analysis, we elected to suspend further recruitment as further use of our prototype simulator could have resulted in negative learning which could have negatively impacted on the care of real patients.
