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There are no randomized data exploring differential effects of digoxin in elderly subgroups.
Clinical studies included in this article define elderly subgroups chronologically as aged 65 years or more to facilitate the analysis of the data.
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Improvements in systems for surveillance of late-life suicidal behavior, particularly attempted suicide, are needed to further develop the foundation on which to evaluate differences in the elderly subgroup, over time, and in different locations, and to better assess changes in response to interventions.
In our elderly subgroup we can confirm these results.
In this study, cardiovascular comorbidity in the elderly subgroup had a negative effect on postoperative mortality.
Besides the age, chronic kidney disease was higher in the elderly subgroup, as it was expected.
The relative risks of the elderly subgroup are reported in Figure 1.
Device type and lead number were different, favoring the elderly subgroup.
Only cardiovascular comorbidity in the elderly subgroup (n = 24; 38%) had a negative effect on postoperative mortality (P = 0.043).
53 There were no major differences in outcome in the elderly subgroup compared to the overall study population.
Furthermore, nearly all early deaths occurred in the elderly subgroup of patients (4 of 5 deaths in patients >70 years).
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