It appears that physician's perceptions of the elderly, strict protocol eligibility criteria, and restrictions on enrolling patients with comorbid conditions may play the biggest roles in preventing the accrual of older patients.
The elderly answered a protocol consisting of a demographic questionnaire, the Mini-Mental State Examination (MMSE) (Folstein et al. 1975), the Problem Coping Mode Scale (PCMS) (Seidl et al. 2001), Satisfaction with Life Scale (SLS) (Diener et al. 1985) and the Positive and Negative Affect Schedule (Diener 1984).
46 In elderly patients, this protocol was applied with or without doses of RT adaptation (Table 1).
In the elderly, PS+PA [per protocol (PP) n = 31], unlike placebo (PP n = 26), significantly improved memory and prevented "winter blues" in a pre post comparison.
Application of the same protocol in elderly subjects resulted in a substantial amelioration of age-related decline in tactile acuity, demonstrating that age-related decline of perception is not irreversible but can be improved by specific stimulation protocols.
A more detailed description of the frailty indicators is given in the study protocol for "Elderly persons in the risk zone" [ 28].
In an amended Italian ATRA and idarubicin (AIDA) protocol for elderly patients, the second and third consolidation cycle of the original protocol was omitted, and intermittent ATRA maintenance was given to all patients.
Correa et al 37 performed a similar longitudinal protocol using elderly women that consisted of twelve weeks of an RT program twice a week followed by twelve weeks of detraining.
Although no significant differences were shown between the PNFG and PG, use of the PNF protocol in elderly women proved to have positive effects; several stabilometric variables demonstrated increased stability and static balance in this group after 12 weeks of exercise.
We present the search space of the TOL and the algorithmic indexes, the experimental protocols for elderly and young participants and finally the data analyses.
