Based on the PTDR framework, we continue to focus on the second "cloud" –further extending and elaboration for learning progressions of scientific explanation.
Another "cloud" on this research field is about the further extending and elaboration for learning progressions of scientific explanation (Braaten and Windschitl 2011; Tang and Chiu 2010).
Rhetorical relations such as causation, elaboration and enablement could aid in tracking the temporal progression of the discourse (17).
One class of transcriptional inhibitors comprises the inhibitors of the CDKs, whose critical role in cell cycle progression and cellular transcription make them attractive targets for the elaboration of new anticancer drugs [ 14].
It requires multi-dimensional views and the integration of molecular interaction networks in the analysis of high-throughput data to define the variation of disease severity and progression, drug sensitivity and resistance, cell growth and differentiation, and pathogenesis elaboration.
BV and NVT proposed the elaboration of a mathematical model based on the GMA power-law formalism of the progression of the disease and with the potential to be used for the design of effective therapies.
Recent studies by the Strober group also highlighted the importance of IL-13Rα2 in the progression of malignant melanoma, where its activation by IL-13 caused TGF-β1 elaboration, which inhibited tumor immune surveillance and favored tumor growth (Fichtner-Feigl et al., 2008b; Strober et al., 2009).
Given that the stage of mammary gland development at the time of carcinogen exposure greatly influences subsequent breast cancer initiation and progression, experimental mouse genetics has recently been applied to delineate progesterone's role in the elaboration of each of these developmental stages.
Progression of MF/SS is accompanied by clonal dominance of the malignant cells, (Vega et al, 2002) leading to the elaboration of Th2 cytokines, (Rook et al, 1997) impairment of the host's immune response, and further tumour cell growth (Girardi et al, 2004; Kim et al, 2005).
Elaboration likelihoodmodel c.
