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Evolutionary elaboration of tissues starts with changes in the genome and location of the stem cells.
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These results prove the importance of microstructured surfaces for the elaboration of tissue engineered biomaterials.
The maintenance of gene expression patterns during the elaboration of tissue development is a key feature of patterning.
Cancer is associated with a pro-coagulant response, particularly through tumour elaboration of tissue factor, a tumour- and host immune-mediated pro-inflammatory cytokine response and platelet activation.
Mechanical property elaboration of engineered tissues is often assumed on the basis of gene and protein characterizations, rather than mechanical testing.
2– 4 A major part of amniote embryogenesis, especially in its early phase, is dedicated to the elaboration of extraembryonic tissues that are essential for survival of the developing embryo (Fig. 1B).
The detailed elaboration of each tissue extraction procedure is described below under the respective heading (a-c).
It seems likely that this PPB mechanism evolved in an early common ancestor of land plants and was important in the elaboration of complex vegetative tissues.
While the oral cavity SCID mouse model of HNSCC requires less than 7 days to obtain measurable tumors, providing limited time for in growth of surrounding tissue, it is possible that the elaboration of secreted MMPs by surrounding tissues and the presence of MMP-2 and MMP-9 in the serum prevent formation of a tumor microenvironment devoid of MMP-2 or MMP-9.
Both inflammatory conditions [ 43] and cancer [ 44] are associated with extensive modulation of local stromal tissue, with elaboration of pro-inflammatory molecules.
Reduced elaboration of MCP-1 in adipose tissue appeared to be responsible, at least in part, because mesenteric fat MCP-1 mRNA levels were reduced (Fig. 6 B), whereas levels in liver were unaffected (data not shown).
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