The sustained hunger neuropeptide profile during restriction, combined with the data on extent and severity of restriction (experiments one and two) on the PRH response suggested that a peripherally generated signal, produced either by the depleted fat or lean tissue, was stimulating appetite and generating the PRH (Dulloo et al., 1997).
The aging process could either deplete the number of precursors or alter their mitotic activity; both would ultimately lead to a reduction in the actual number of newly born cells.
Thus, the mainstay of treatment targets this dependence, combining mechanisms to either deplete the AR of ligand or through the use of direct AR antagonists.
So, amid budget negotiations, tea party factions tacked provisions onto spending bills that would've either depleted the healthcare law of any funding or delayed the law's full implementation.
Consistent with the functional relationship between Cdk5rap2 and Pericentrin, knock-down of either protein depletes the neural progenitor pool and triggers cell cycle exit, leading to premature neuronal differentiation without substantial apoptosis in the developing mouse neocortex of an in utero electroporation model (Table 2) [ 70].
Russia, along with Taiji, Japan, and Cuba, is becoming a major source of captive marine mammals, as other sources around the world have either been depleted or closed to the dolphin captivity trade by activists and governments.
To determine the potential role of these two myeloid populations in regulating vascular remodeling during infection, we compared the effects of either depleting both populations (using Gr-1) or just Ly6G+ neutrophils (using 1A8).
Well, for much longer than we've had Obamacare, Medicaid has been paying for nursing home care and, sometimes, home care for people who are very frail or disabled and whose income and assets have either been depleted by the costs of care or who never had much money to begin with.
HeLa nuclear extracts were immunodepleted of either PC4 or CK2 and the depleted extracts analyzed by Western Blot to assess the efficiency of depletion (Supplemental Figure S1A).
Additionally, the supernatants of either mutp53 depleted or kineret pretreated cancer cells abolishes the IL-1β-induced HUVEC endothelial cell monolayer permeability, a hallmark of early angiogenesis [ 6].
