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Cross-talk between mediators must be considered and it is possible that multiple proteins will need to be targeted either sequentially or together.
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Several currently ongoing and planned adjuvant trials are incorporating gemcitabine (either sequentially or in combination) into anthracycline/taxane regimens.
Investors should be extremely wary of companies that are experiencing a decline in gross margins (either sequentially or year-over-year).
Because people can have multiple long-term relationships (either sequentially or concurrently) [20], the experimental design was consistent with human relationship patterns.
The antracycline chemotherapy was used either sequentially or as a sandwich scheme.
Letters within the stimulus items were delivered either sequentially or simultaneously.
Such an environment may be an infected host who is treated either sequentially or simultaneously with multiple antibiotics.
To test this, kan1 and arf4 mutations were introduced sequentially or together into the 35S pro ::FIL GR background and their phenotype assessed following continuous exposure to DEX.
To generate subcellular localization fusion vectors used for experiments in Figure 4, the appropriate cloning vector and an mEmerald fusion vector were digested, either sequentially or doubly, with the appropriate enzymes and ligated together after gel purification.
To generate fusion vectors, the appropriate cloning vector and an EGFP fusion vector were digested, either sequentially or doubly, with the appropriate enzymes and ligated together after gel purification.
Traditionally, these problems have been solved either sequentially or in a combined manner.
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