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Accordingly, we compared patients receiving lapatinib and trastuzumab (either sequentially or concomitantly) after completion of local therapy with individuals who only received trastuzumab plus/minus chemotherapy and a historical control group of HER2-positive subjects without any further targeted therapy.
Patients in the 'both agents' category may have received the anti-HER2 agents either sequentially or concomitantly.
Although the potential benefits of adding taxanes to anthracycline-based regimens remain controversial in terms of long-term outcomes (Bear et al, 2006), regimens combining anthracyclines with taxanes, either sequentially or concomitantly, are widely used.
Bartsch et al (2012) showed that among 80 patients with brain metastases from HER2-positive breast cancer, use of trastuzumab and lapatinib, either sequentially or concomitantly, with or without chemotherapy was significantly associated with a 72% reduction in risk of death compared with trastuzumab-based treatment alone (P=0.012).
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Several currently ongoing and planned adjuvant trials are incorporating gemcitabine (either sequentially or in combination) into anthracycline/taxane regimens.
Investors should be extremely wary of companies that are experiencing a decline in gross margins (either sequentially or year-over-year).
Because people can have multiple long-term relationships (either sequentially or concurrently) [20], the experimental design was consistent with human relationship patterns.
The antracycline chemotherapy was used either sequentially or as a sandwich scheme.
Letters within the stimulus items were delivered either sequentially or simultaneously.
Such an environment may be an infected host who is treated either sequentially or simultaneously with multiple antibiotics.
The pairs seem to be able to build several nests sequentially or concomitantly before actively using a nest.
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CEO of Professional Science Editing for Scientists @ prosciediting.com