Olfactory ensheathing cells have shown surprising promise in healing spinal-cord injuries in a field dominated by far better-funded efforts, principally stem-cell transplants and experiments to stimulate nerve growth through drugs.
Initial recruitment efforts principally targeted the Matabele, who made up about 20% of the colony's black population, because they enjoyed a popular reputation among whites for being great warriors; the unit was therefore originally called the "Matabele Regiment".
The international validation efforts, conducted principally by the Systemic Lupus Erythematosus International Collaborating Clinics group, have produced both activity and damage indices for this disease.
These increases in fishing effort were principally a result of improving technology and increasing prices.
For people, domestic animals and especially wildlife, in many situations around the world it is difficult to identify all the causes of detectable shifts in disease occurrence and, correctly, efforts are directed principally at mitigation of the disease and at effective control.
She said she would work to raise money principally for efforts to combat multiple sclerosis, which afflicts her 42-year-old daughter, Muffy.
One could also argue that Popper's critique of Marxism applies principally to efforts to defend the ideology on scientific grounds.
His efforts would be directed principally at trying to open markets such as South Korea, where there were tight restrictions on investment by UK companies, working both through bilateral agreements and through bodies such as the World Trade Organisation.
Writing in the New York Times last month, Laura Pappano offered a thoughtful analysis of the efforts by public colleges - principally public flagship universities - to find new sources of revenue, diversify their student bodies, and expand their national reputations.
This, in turn, had provoked an immense effort by the Democrats, principally associated with Bill Clinton to claw back a majority by tactical accommodations while preserving a commitment to social justice and internationalism.
Summit organizer Mark Gerzon, a Malibu producer, said the bilateral event was principally an effort to dispel negative stereotypes that Americans and Soviets have of each other, both on and off screen.
