However, we feel strongly that the clonal data presented, which represents a large amount of effort, establishes that in multiple regions of the midgut, cells are normally replaced only by the local ISCs from that region.
But the opposition's efforts to establish that administration and a unified military command, and to obtain greater military support from the West, remain nascent at best.
These tollbooths, once considered the murder site of Sonny Corleone in Mario Puzo's The Godfather, were closed in 1978 as part of Governor Hugh Carey's efforts to establish that year's state budget.
The present findings provided the first effort to establish that DMC could partially protect the endothelial dysfunction of aorta in HF diet rats via upregulating the expression of eNOS.
But his efforts established the intimacy, flexibility and expressiveness that made the string quartet a medium capable of encompassing his own congeniality and craft, Beethoven's stormy spirit, Shostakovich's hidden turmoil and Elliott Carter's fearsome concatenations.
Given that it was both critical to his theory of natural selection and directly counter to much contemporary thinking, it should not be surprising that Darwin (1859) expended considerable effort in attempting to establish that variation is, in fact, ubiquitous.
While considerable effort has gone into establishing that EndMT occurs and plays a role in a variety of pathologic conditions, the regulation of this process remains poorly understood.
Recent research efforts have established that Laves phase reinforced gamma titanium aluminides (i.e. γ+Laves) offer significant potential as oxidation resistant coating in high-temperature structural applications.
Still, much as Rosie the Riveter irreversibly changed the lives of American women after World War II, Libyan women say their war effort established facts on the ground that cannot be easily undone.
Fitful efforts over the years established that cellular life and organismal development depend on adenosine methylation (5 7) but have identified only a handful of methylated positions (8), and, consequently, further functional investigations were limited.
