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When the efficiency of cellular uptake was examined after Hoechst staining, almost 100% of the cells exhibited the GFP signal, revealing that rHoxc8 can traverse the cellular membrane of COS-7 cells efficiently, suggesting that the rHoxc8 could be applied in the development of efficient and useful delivery vectors for therapeutic molecules.
Other cell types did not cleave the biosensor efficiently suggesting that cellular proteinases distinct from furin-like PCs did not contribute significantly to the biosensor cleavage.
None of these other cosmids complemented the un-7 mutation efficiently suggesting that one of the ORFs unique to H121G9 was un-7+.
Rep2 was also able to replicate this ITR efficiently, suggesting the poorly conserved nature of the GAGY repeat within the ITR5 spacer prevents a critical DNA-protein interaction with Rep2 necessary for replication.
This clone was also found to neutralize LT most efficiently, suggesting that its N-glycosylation contributes to toxin neutralization.
Moreover, the gene therapy suppressed breast cancer growth in nude mice efficiently, suggesting that AAV-mediated, Dox regulatable sTRAIL expression is a promising strategy for cancer gene therapy.
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Like the app business where abundance creates a need for more human-powered guidance and suggestions (see Jean-Louis's idea of a Guide Michelin for Apps), book sections of magazines and newspapers will have to adapt and find ways to efficiently suggest e-readings to their audience.
Under the new system, software will analyze the entire Norfolk network every hour and, to keep traffic flowing efficiently, suggest changes in speed, routing and train meeting places.
Also, NPV can be extremely high, indicating that the release policy can efficiently suggest that the released individuals are likely to be true negatives.
In this Article, we now show how molecular modeling can be used to shed light on molecular mechanisms of anesthetic action as well as more efficiently suggest in vitro mutations for testing of molecular models.
More abundant mRNAs are more efficiently downregulated, suggesting a concentration effect in transcript targeting.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com