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As an internal control for MHC-I internalization, these ΔY-derived DCs efficiently internalized endogenously-expressed wild-type Kk molecules (33% internalization at 30 minutes of chase), albeit not as rapidly as observed for KbWT DCs (Figure 2C).
In agreement with previously reported results [13], the plasmid-cured avirulent Y. pseudotuberculosis strain YPIII was efficiently internalized by control HeLa cells (69% internalization) (Figure 3B), whereas the corresponding wild-type strain remained largely extracellular (11% internalization) (Figure 3B).
This is supported by the observation of Patil et al. [46], who examined internalization of cerium oxide nanoparticles and found that negatively charged nanoparticles more efficiently internalized into adenocarcinoma lung cells than the positively charged.
The strong fluorescence from the cytoplasm confirmed that the QDs were efficiently internalized by the cells.
In vitro studies showed that protamine nanocapsules were efficiently internalized by macrophages without eliciting significant toxicity.
A2 was efficiently internalized into both cell lines via at least two different mechanisms.
The obtained results showed that neutral PC-liposomes are the most efficiently internalized by HeLa cells.
Cell culture analysis by microscopy and flow cytometry revealed that the prodrug nanogels were efficiently internalized by tumor cells.
The nanocapsules were demonstrated to be efficiently internalized into the cells and to release the protein in the reducing cytosol.
The vector was quickly and efficiently internalized by the cells, and endocytosis was the most productive uptake mechanism for silencing.
We found that the CuDox complex was efficiently internalized by mammary carcinoma cells after release from LTSLs.
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CEO of Professional Science Editing for Scientists @ prosciediting.com