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SNCG derived from RT-treated dying tumor cells may moderate the stimulation of DCs, similar to smDCs, with low expression of phenotypic maturation ligands and the induction of immunosuppressive cytokines, thereby rendering the DCs incapable of efficiently interacting with T cells or eliciting fully immunogenic responses.
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Atypically for GoLoco Gα interactions, Pins efficiently interacts with both the GDP-loaded (inactive) and the GTP-loaded (activated) forms of Gαo [ 4– 6]; in other proteins, the exclusive interaction of Gα-GDP with GoLoco motifs has been described [ 3].
While WT Ngn3 could efficiently interact with Fbw7, the interaction was severely impaired when Ser183 was mutated (Ngn3-AA and Ngn3-AS; Figure 4I, right panel).
These interactions might enable Ste11 to efficiently interact with Pbs2 that is associated with Sho1.
At higher concentration of ethanol, there is a higher efficiency of desorption due to the incapability to efficiently interact with HA molecules that contain numerous functional groups.
New technologies allow large groups to efficiently interact via the internet.
This result further demonstrates the binding specificity of the RBFOX1/2 binding motif and suggests that the SRSF1 motif would not efficiently interact with RBFOX1/2 proteins.
The goal of Gehlenborg's research is to improve human health by developing computational techniques and interfaces that enable scientists and clinicians to efficiently interact with biomedical data.
Results from a user study showed that users are able to efficiently interact with the tool to analyze relationships between pupillary response and task execution.
It was also proven to efficiently interact and condense plasmid DNA, forming a stable, small (∼100 nm) and positively charged (+28.6 mV) complex.
This increment can be explained by the facts that the 3D-3D structure with a high specific surface area is beneficial to bacteria growth, and that the in-situ formed microbially reduced GO is efficiently interacted with the electrochemically active bacteria.
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