The basal E. coli protein homeostasis (proteostasis) network capacity is often insufficient to efficiently fold overexpressed proteins.
Thus the available concentration of SR 25989 could have been insufficient to efficiently inhibit angiogenesis activators participating to primary tumour development.
10 These authors considered that loss of chromosome 3 was insufficient to efficiently discriminate high-risk patients from low-risk patients.
Diabetic patients however cannot control their postprandial blood glucose efficiently due to the insufficient insulin secretion or response, which results in postprandial hyperglycemia and it is an important contributing factor for diabetic complications [ 22].
While PON1R192 hydrolyzes paraoxon approximately 9-times as efficiently as PON1Q192, the efficiency is insufficient to provide in vivo protection against paraoxon/parathion exposure.
He alleges the diversion over 14 years of $750 million violates a provision in the U.S. Constitution authorizing Congress to set up a patent system "to promote the progress of science and the useful arts" because it leaves insufficient funds to efficiently process patent applications, lengthening the approval time.
While highest k m value (98.5349) was observed in C/N 25 compared to other reactors, showed that the microorganisms does not decomposed the organic matter efficiently, might be due to insufficient oxygen as the air could not penetrate inside the waste mixture.
Additionally, the cost of the project continued to escalate because of insufficient funding to most efficiently move forward and complete the project.
It has been suggested that VP16 might not be efficiently transported along axons such that insufficient amounts reach the neuronal cell body (Kristie & Roizman, 1988; Kristie et al., 1999).
The synthesis of UNCD films using the uniquely focused plasma jet was confirmed to efficiently compensate for the sluggish kinetics and insufficient density of plasma species during the LPLT synthesis.
